![]() Curcumin doses ranged from between 90 and 4,000 mg/day, with significant improvements found in three of the five studies. Five databases were searched (CINAHL, Cochrane Library, PubMed, SCOPUS, Web of Science) with five studies identified, each using different forms of curcumin and validated cognitive screening measures, meeting inclusion criteria. Following PRISMA 2009 guidelines, a systematic review was conducted to identify randomized, placebo-controlled trials investigating the effects of curcumin supplementation on cognitive function in older adults (>50 years). Questions remain surrounding curcumin’s bioavailability and the mechanism by which it may exert neuroprotective effects. Curcumin is a polyphenol present in turmeric and is credited with anti-inflammatory, antioxidant, and chemoprotective properties.
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